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Opioids and Overdoses

Naloxone: English and Spanish Instructions in the right column

  • Naloxone temporarily reverses an opiate overdose by blocking the brain’s opiate receptors, allowing breathing to be restored.
  • The duration of the effect varies, but typically lasts between 30 and 60 minutes. After the opiate receptors are no longer blocked by Naloxone, the individual may resume overdosing. It is important to call 911, even if it appears that the individual is no longer overdosing.
  • Naloxone only temporarily reverses overdoses due to opiate prescription pain relievers (such as Oxycontin and hydrocodone) and heroin. Administering Naloxone to someone overdosing on other drugs will not have an effect.